Town of Muldraugh, Kentucky, United States, 9am, 11 of July 1993, you wake up and turn on the radio, like every day, but this time you hear about "the Knox Event". Then you look through the window and see your neighbour, but he is acting strange, knocking on the door of his own house with his head. He is infected, and you will be soon too.

Año 149 a.C., batalla de Cartago, tú eres un legionario/a romano, y tú y el resto del ejército debéis ganar la batalla para derrotar a Aníbal y a los cartagineses, y alzarse con la victoria de Roma. Él es un Centurión, es mejor seguir sus órdenes.