Lois Patrice Griffin is a character in the animated comedy series Family Guy. She first appeared in the episode "Death Has a Shadow" on January 31, 1999. Alex Borstein voices the character and has won a Primetime Emmy Award for her work. Lois is a housewife and piano instructor who is married to Peter Griffin and has three children: Meg, Chris, and Stewie. She has a New Yorker accent and comes from a wealthy family.